Patents

US 7,399,627 (.pdf file 3.6 MB)
Transformation System in the Field of Filamentous Fungal Hosts.
M.A. Emalfarb, R.P Burlingame, P.T. Olson, A.P. Sinitsyn, M. Parriche, J.C. Bousson, C.M. Pynnonen, P.J. Punt, C. van Zeijl

US 7,122,330 (.pdf file 3.71 MB)
High-Throughput Screening of Expressed DNA Libraries in Filamentous Fungi.
M.A. Emalfarb, P.J. Punt, C. van Zeijl, C. van den Hondel

US 6,573,086. 2003. (.pdf file 4.12 MB)
Transformation System In The Field Of Filamentous Fungal Hosts.
M.A. Emalfarb, R.P. Burlingame, P.T. Olson, A.P. Sinitsyn, M. Parriche, J.C. Bousson, C.M. Pynnonen, P.J. Punt, C. van Zeijl

WO 01/79558. 2001. (.pdf file 5.41 MB)
High-Throughput Screening of Expressed DNA Libraries in Filamentous Fungi.
M.A. Emalfarb, P.J. Punt, C. van Zeijl, and C. van den Hondel.

PCT WO 01/25468. 2001. (.pdf file 5.22 MB)
High Throughput Screening of Expressed DNA Libraries in Filamentous Fungi.
M.A. Emalfarb.

PCT WO 00/20555. 2000. (.pdf file 4.6 MB)
Transformation System In The Field Of Filamentous Fungi.
M.A. Emalfarb, R.P. Burlingame, P.T. Olson, A.P. Sinitsyn, M. Parriche, J.C. Bousson, C.M. Pynnonen, and P.J. Punt.

US 6,015,707. 2000. (.pdf file 2.11 MB)
Treating cellulosic materials with cellulases from Chrysosporium.
M.A. Emalfarb, A. Ben-Bassat, and A.P. Sinitsyn.

US 5,811,381. 1998. (.pdf file 2.08 MB)
Cellulase compositions and methods of use.
M.A. Emalfarb, A. Ben-Bassat, R.P. Burlingame, V.M. Chernoglazov, O.N. Okunev, P.T. Olson, A.P. Sinitsyn, and I.V. Solovjeva.

Presentations

"Gene Discovery, Gene Expression, and Product Manufacturing Using an Integrated Fungal Host System". Presented by Richard Burlingame (invited speaker). Building Bridges in Bioscience Innovation: Bridges in Innovation I, BioFlorida meeting. Boca Raton, Florida. April 30, 2002.

"Developing Value-added Biological Products from the World's Gene Pool". Presented by Mark Emalfarb (invited speaker). Treasure Coast Venture Forum. Palm City, Florida. April 18, 2002.

"Chrysosporium lucknowense, a New Fungal Host for Protein Production and High-Throughput Screening". (.pdf file 937 KB) Cora van Zeijl, Jeffrey Bartels, Peter Punt, Mark Emalfarb, Richard Burlingame, Phillip T. Olson, Christine M. Pynnonen, Arkady Sinitsyn and Cees van den Hondel. Oral and poster presentations at 6th European Congress on Fungal Genetics. Pisa, Italy. April 6-9, 2002.

"Study of Cellulase Adsorption on Indigo and Cellulose". A.V. Gusakov, A.P. Sinitsyn, A.V. Markov, O.A. Sinitsyna, and N.V. Ankudimova. Second International Symposium on Biotechnology in Textiles. Athens, Georgia. April 3-6, 2002.

"Developing Value-added Biological Products from the World's Gene Pool". Presented by Mark Emalfarb (invited speaker). Florida Venture Capital Conference. Miami, Florida. January 30-31, 2002.

"Gene Discovery to Manufacturing in One Beast - The C1 Integrated Screening-Expression System". Presented by Richard Burlingame (invited speaker). Commercializing Advances in Microbiology: A Biotechnology Investor Forum. ASM Resources, Inc. Washington, D.C. January 29, 2002.

"Developing Value-added Biological Products from the World's Gene Pool". Presented by Mark Emalfarb (invited speaker). Commercializing Advances in Microbiology: A Biotechnology Investor Forum. ASM Resources, Inc. Washington, D.C. January 29, 2002.

"Dyed Substrates for Analysis of Enzyme Activities in Animal Feed". I.N. Zorov and A.P. Sinitsyn. 13th European Symposium of Poultry Nutrition and Ascites Workshop, Blankenberge, Belgium, September 30 - October 4, 2001.

"The Use of Tergotometers to Evaluate Cellulase". Presented by Daniel B. Shook. American Association of Textile Chemists and Colorists Regional Meeting. Orlando, Florida. August, 2001.

"Chrysosporium lucknowense, a New Fungal Host for Protein Production". (.pdf file 91 KB) Cora van Zeijl, Peter Punt, Mark Emalfarb, Richard Burlingame, Phillip T. Olson, Christine M. Pynnonen, Arkady Sinitsyn, M. Parriche, J-C Bousson and Cees van den Hondel. Twenty First Fungal Genetics Conference. Genetics Society of America. Asilomar, California. March 15-18, 2001.

"GMO versus non-GMO Strategy for a Global Enzyme Company". D.F. Tiknomirov and M.A. Emalfarb. Third European Symposium on Feed Enzymes. Noordwijkerhout, the Netherlands. May 8-10, 2000.

"Development of Micro Assay for Investigation of Cellulase Abrasive Activity and Backstaining". A.P. Sinitsyn, A.V. Gusakov, S.G. Grishutin, and O.A. Sinitsyna. Symposium on Biotechnology in Textile Industry. Povoa de Varzim, Portugal. May 3-7, 2000.

"Saccharifying and Topolytic Activities of Various Cellulase Enzymes". A.P, Sinitsyn, A.V. Gusakov, A.G. Berlin, N.N. Popova, A.V. Markov, A.A. Skomarovsky, O.A., Sinitsyna, and S.G. Grishutin. 219th ACS National Meeting, San Francisco, California. March 26-30, 2000.

"A Comparative Analysis and Evaluation of Various Cellulases and Their Relative Effect on Tensile and Tear Strength Performance of Denim." Dennis C. Scheer, Daniel B. Shook, Frank A. Bae, Arkady P. Sinitsyn, and Nonna N. Popova. American Association of Textile Chemists and Colorists. International Conference and Exhibition. Charlotte, North Carolina. October 12-15, 1999.

"Biobleaching of Industrial Softwood Kraft Pulps by Novel Xylanse Enzymes". G.P. Alexandrova, S.A. Medvedeva, V.A. Petrenev, I.V. Sergeeva, A.P. Sinitsyn, and O.N. Okunev. Tenth International Symposium of Wood and Pulp Chemistry, Jokohama, Japan. June 7-10, 1999.

"The Mechanism of Cellulase Enzymes for Textiles: the Enzymologist's View". A.P. Sinitsyn, A.V. Gusakov, and O.A. Sinitsyna. American Association of Textile Chemists and Colorists Symposium on Emerging Technologies & Trends in Garment Wet Processing. New Orleans, Louisiana. May 13-14, 1999.

"Use of Enzymes in Kraft Pulp Bleaching". G.P. Alexandrova, S.A. Medvedeva, V.A. Babkin, V.A. Petrenev, I.V. Sergeeva, A.D. Sergeev, A.P. Sinitsyn, and O.N. Okunev. Fifth European Workshop of Lignocellulosics and Pulp. Aviero, Portugal, August 30 - September 2, 1998.

Publications

J.C. Verdoes, P.J. Punt, R. Burlingame, J. Bartels, R. van Dijk, E. Slump, M. Meens, R. Joosten, and M. Emalfarb. 2007. A dedicated vector for efficient library construction and high throughput screening in the hyphal fungus Chrysosporium lucknowense (.pdf file 10.3 MB). Industrial Biotechnology, GEN Publishing Inc., A Mary Ann Liebert Inc. Company, vol. 3 no. 1: 48-57.

A.V. Gusakov, T.N. Salanovich, A.I. Antonov, B.B. Ustinov, O.N. Okunev, R. Burlingame, M. Emalfarb, M. Baez, and A.P. Sinitsyn. 2007. Design of Highly Efficient Cellulase Mixtures for Enzymatic Hydrolysis of Cellulose (.pdf file 364 KB). Wiley Periodicals, Inc., 39p.

A.P. Sinitsyn, A.V. Gusakov, S.G. Grishutin, S.A. Sinitsyna, and N.V. Ankudimova. 2001. Application of Microassay for Investigation of Cellulase Abrasive Activity and Backstaining. Journal of Biotechnology, 89: 233-238.

A.V. Gusakov, A.G. Berlin, N.N. Popova, O.N. Okunev, O.A. Sinitsyna, and A.P. Sinitsyn. 2001. A Comparative Study of Different Cellulase Preparations in the Enzymatic Treatment of Cotton Fabrics. Applied Biochemistry and Biotechnology. 88: 119-126.

G.P. Alexandrova, S.A. Medvedeva, A..P. Sinistyn, and O.N. Okunev. 2000. Changes of the Structural Composition of Hardwood Kraft Pulp during Bleaching. Applied Biochemistry and Microbiology (Moscow). 36: 245-249.

A. Gusakov, A. Sinitsyn, S., Grishutin, D. Tikhomirov. D. Shook, D. Scheer, and M. Emalfarb. 2000. Microassays to Control the Results of Cellulase Treatment of Denim Fabrics. Textile Chemists and Colorist & American Dyestuff Reporter. 32: 42-47.

E.I. Dzedsyulya, E.G. Becker, O.N. Okunev, and A.P. Sinitsyn. 1999. Feruloyl Esterase from Aspergillus sp.: Purification. Properties and Action on Natural Substrates. Biochemistry (Moscow). 45: 405-410.

A.V. Gusakov, A.P. Sinitsyn, A.G. Berlin, N.N. Popova, A.V. Markov, O.N. Okunev, D.F. Tikhomirov, and M.A. Emalfarb. 1998. Interaction Between Indigo and Adsorbed Protein as a Major Factor Causing Backstaining During Cellulase Treatment of Cotton Fabrics. Applied Biochemistry and Biotechnology, 75: 279-293.

O.F. Castellanos, A.P. Sinitsyn, and E. Y. Vlasenko. 1995. Evaluation of Hydrolysis Conditions of Cellulosic Materials by Penicillium Cellulase. Bioresource Technology, 52: 109-117.

O.F. Castellanos, A.P. Sinitsyn, and E. Y. Vlasenko. 1995. Comparative Evaluation of Hydrolytic Efficiency toward Microcrystalline Cellulose of Penicillium and Trichoderma cellulases. Bioresource Technology 52: 119-124.

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